Product Description

Vitamin K3 58-27-5 Menadione//Vitamin B2 83-88-5 riboflavin//Vitamin B1 59-43-8//532-43-4 vitaminb(sub1)nitrate//67-03-8 Thiamine hydrochloride

Introduction

Product name	Thiamine hydrochloride
Cas No.	67-03-8
Molecular Formula	C₁₂H₁₈Cl₂N₄OS
Appearance	White powder

Function

Vitamin B1,also known as thiamin or Thiamine, is a vitamin found in food, and manufactured as a dietary
supplement and medication. Among food sources are whole grains, legumes, and some meats and fish.
Refined grains lose much of their thiamine and cereals and flours are enriched with thiamine in many countries.
Supplements and medications are available to treat and prevent thiamine deficiency and disorders that result
from it, including beriberi and Wernicke encephalopathy. Other uses include the treatment of maple syrup urine
disease and Leigh disease. They are typically taken by mouth, but may also be given by intravenous or
intramuscular injection.to promote growth; help digestion, especially in carbohydrate digestion; to improve
mental health; maintain nerve tissue, muscle, normal heart activity; relieve motion sickness, motion sickness;
can ease the pain related to dentalsurgery; contribute to the band Like herpes (herpes zoster) treatment.
Plays an important roletomaintain normalnerve conduction,heartanddigestive systemto normalactivities.

Application

* Metabolic disorders. Taking thiamine by mouth helps correct metabolic disorders associated with genetic
diseases, including Leigh's disease, maple syrup urine disease, and others.
* Thiamine deficiency. Taking thiamine by mouth helps prevent and treat thiamine deficiency.
* Brain disorder due to thiamine deficiency (Wernicke-Korsakoff syndrome)Thiamine helps decrease risk
and symptoms of a specific brain disorder called Wernicke-Korsakoff syndrome (WKS)This brain disorde
r is related to low levels of thiamine (thiamine deficiency)
* Athletic performance.Some research suggest taking thiamine together with pantethine and pantothenic
acid(vitamin B5) does not improve muscle strength or endurance in athletes.
* Preventing cervical cancer. Some research suggests that increasing intake of thiamine from dietary and
supplemen sources,along with other folic acid,riboflavin,vitaminB12,might decrease the risk precancerous
spots on the cervix.
* Cataracts. High thiamine intake as part of the diet is associated with reduced risk of developing cataracts.
* Kidney disease in people with diabetes.Early research show that taking high-dose thiamine (100 mg three
times daily) for 3 months decreases the amount of albumin in the urine in people with type 2 diabetes.
Albumin in the urine is an indication of kidney damage.

Specification

Manufacturing date	Apr 27 , 2020	Reporting date	May 3 , 2020
Retest date	Apr 26 , 2023	Articl No.	07103
Package	25kg per drum	package size	410*550(mm)
Ref. pharmacopoeia(s)	BP2018, USP42	Quantity	500kg

	Test Item	Specification	Result
BP2018	appearance	white or almost white, crystalline powder or colourless crystals	white crystalline powder
	PH	2.7~3.3	3.0
	Water	≤5.0%	3.38%
	sulphated ash	≤0.1%	0.02%
	sulphates	≤300ppm	<300ppm
	heavy metals	≤20ppm	<20ppm
	Assay(on anhydrous basis)	98.5%~101.0%	99.5%
USP42	identification	A:IR absorption;B:test of chloride.	comply
	absorbance of solution	≤0.025	0.016
	limit of nitrate	no brown ring produced at the junction of the two layers	comply
	ph	2.7~3.4	3.2
	water	≤5.0%	3.38%
		≤0.2%	0.02%
		≤1.0%	0.06%
	Assay(on anhydrous basis)	98.0%~102.0%	99.7%